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Ella
Puppy
Joined: 03 Jan 2008
Posts: 28
Location: Netherlands
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 Posted: Mon Jan 14, 2008 3:33 am Post subject: |
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| shadyblueamstaffs wrote: |
| Meadowbrooks wrote: |
| It is just in all the lines. I think the lines that we don't think it is in, IS. People just kept it on a down low. Just like they are doing with hearts problems.IMO |
Considering there are five major lines in amstaffs, just from the breedings I named, that about covered all five lines, so you are exactly right Larry, ataxia is in every line.
I wish more people would be open about health issues becasue it would really help to fix the problems. I must be dreaming to think that could happen some day. LMFAO |
I didn't know ruffian Bo Tie& Tux was affected! Hope they find that marker real soon so we can test our dogs... |
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shadyblueamstaffs
Alpha Dog
Joined: 15 Dec 2007
Posts: 1111
Location: Missouri USA
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| Posted: Tue Feb 05, 2008 3:54 pm Post subject: |
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http://www.amstaff.org/health.htm
Update on Research into the Genetic Cause of Hereditary Ataxia in American Staffordshire Terriers – January 2008
This is a brief update to let you know that we are continuing to make good progress with our research into Hereditary Ataxia in American Staffordshire Terriers. The last update I gave reported that we had established linkage between the disease and a limited region of a chromosome. This region was large, too large to identify one particular gene that could be causing the disease. In order to address this problem, we submitted a grant proposal to the AKC Canine Health Foundation requesting funding for the next step in our research – fine mapping of the linked region and sequencing of candidate genes. The grant has been approved and we expect to have the funding available to us shortly. In the interim, with the support of the STCA, we have genotyped a much larger number of dogs (nearly 100) and added in closely spaced markers over the linked region. As a result, we have been able to narrow down the area of linkage and we are getting ready to sequence one particular gene that could be linked to the disease. Over the next year we will work on the possible candidate genes in the linked region with the hope that they will lead us to the causative mutation and hence to a genetic test. If you know anyone with an affected dog, we would love to hear from them, and if you would like to make a donation to support the research, please contact Faith Beiser. Thank you all for your continued support and we hope that 2008 will be a productive year. |
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shadyblueamstaffs
Alpha Dog
Joined: 15 Dec 2007
Posts: 1111
Location: Missouri USA
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| Posted: Sun Feb 10, 2008 7:12 pm Post subject: |
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| Hey there funny guy, did you read the post right before the one you posted. LOL |
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Meadowbrooks
Alpha Dog
Joined: 12 Dec 2007
Posts: 1480
Location: va
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| Posted: Mon Feb 11, 2008 5:44 am Post subject: |
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ROFL. Sorry. LOL I thought it was something new. Glad you caught that.lol and YES, I read this post. I was doing a bunch of things and just did it *beep* it.lol I always read what you post. Well, most of the time.  |
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ironheartk9s
Puppy
Joined: 08 Jan 2008
Posts: 2
Location: Smithville, Texas
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| Posted: Mon Jun 09, 2008 9:52 pm Post subject: Pedigrees |
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I would appreciate pedigrees of the dogs below. I have Bo Tie & Tux and Sentinals Just E Zee, but I would really appreciate the rest.
| shadyblueamstaffs wrote: |
Ruffian Bo Tie & Tux's was affected.
Ruffian Bo Tie & Tux's X Sentinel's Just E Zee This breeding produced alot of ataxic offspring. Every puppy was either an affected or a carrier, depending on if just e zee was an affected or carrier.
Ruffian Blue bandit of york is one of the offspring, and he was either affected or a carrier. If Sentinel's Just E Zee was affected as well, then all the offspring would be affecteds from that breeding. She was at the very least a carrier.
Tonkawa Devil Dan X Brandy Fleming- this breeding produced ataxic offspring.(this is the breeding bo tie & tux is from)
Garret's Revelation X Little Rascals Rowdy Roxanne- this breeding produced ataxic offspring.
Other breedings that produced ataxic offspring:
Tex's Felix X Haure
Tex's Hey Paco Diablo X Irma Du Grande Molosse
Irun Des Eaux Rouges X Look Du Grande Molosse
Jerry Du Grande Molosse X Laike Du Grande Molosse
I also have these pedigrees for anyone not familiar with them.
Once in a blue moon was also bred and produced ataxic pups. |
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